UNIVERSAL IMMUNITY TO INFLUENZA MUST OUTWIT IMMUNE EVASION

Universal immunity to influenza must outwit immune evasion

Although an influenza vaccine has been available for 70 years, influenza virus still causes seasonal epidemics and worldwide pandemics.Currently available vaccines elicit strain-specific antibody responses to the surface haemagglutinin (HA) and neuraminidase (NA) proteins, but these can be ineffective against serologically-distinct viral variants a

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A Marine Anthraquinone SZ-685C Overrides Adriamycin-Resistance in Breast Cancer Cells through Suppressing Akt Signaling

Breast cancer remains a major health problem worldwide.While chemotherapy represents an important therapeutic modality against breast cancer, limitations in the clinical use of chemotherapy remain formidable because of chemoresistance.The HER2/PI-3K/Akt pathway has been demonstrated to play a causal role in conferring a broad chemoresistance in bre

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